PMU17 COST-EFFECTIVENESS OF IMPLEMENTING ROUTINE HEARING SCREENING USING A TABLET AUDIOMETER FOR PEDIATRIC CYSTIC FIBROSIS PATIENTS RECEIVING HIGH-DOSE AMINOGLYCOSIDES

The role of routine hearing screening in children with cystic fibrosis on aminoglycosides: A systematic review.

OBJECTIVE To review the role of routine hearing screening for sensorineural hearing loss (SNHL) in children with cystic fibrosis (CF) who have been on aminoglycoside therapy. DATA SOURCES PubMed, Cochrane, Scopus, and Ovid databases. REVIEW METHODS A systematic review of the literature was performed in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyse...

Cost effectiveness of antenatal screening for cystic fibrosis.

OBJECTIVE To estimate the cost effectiveness of different antenatal screening programmes for cystic fibrosis. SETTING Antenatal clinics and general practices in the United Kingdom. DESIGN Four components of the screening process were identified: information giving, DNA testing, genetic counselling, and prenatal diagnosis. The component costs were derived from the literature and from a pilot...

Cost-effectiveness of 4 neonatal screening strategies for cystic fibrosis.

OBJECTIVES The purpose of this work was to assess the costs of 4 neonatal screening strategies for cystic fibrosis in relation to health effects. In each strategy, the first test was the measurement of serum concentration of immunoreactive trypsin. The second step consisted of either a second immunoreactive trypsin test (strategy 1) or a multiple mutation analysis (strategy 2). In strategies 3 ...

COST-EFFECTIVENESS OF CARRIER SCREENING FOR CYSTIC FIBROSIS IN AUSTRALIA Short title: Cost-effectiveness of CF carrier screening

Occurrence and risk of cochleotoxicity in cystic fibrosis patients receiving repeated high-dose aminoglycoside therapy.

Cystic fibrosis (CF) patients receive repeated courses of aminoglycoside therapy. These patients would consequently be expected to be more susceptible to cochleotoxicity, a recognized side effect with single courses of aminoglycoside therapy. The primary aim of this retrospective study was to establish the incidence and severity of auditory deficit in CF patients. Standard (0.25- to 8-kHz) and ...